Fmoc-(R)-3-amino-4-(tert-butoxy)butanoic acid - Names and Identifiers
Name | (3R)-4-tert-butoxy-3-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}butanoic acid
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Synonyms | Fmoc-β-HoSer(tBu)-OH Fmoc-β-HoSer(OtBu)-OH Fmoc-L-β-HomoSer(tBu)-OH FMOC-L-BETA-HOMOSERINE(OTBU) Fmoc-L-Beta-Homoserine(Otbu) O-tert-Butyl-N-Fmoc-L-beta-homoserine Fmoc-(R)-3-amino-4-(tert-butoxy)butanoic acid (9H-Fluoren-9-yl)MethOxy]Carbonyl β-HoSer(tBu)-OH (3R)-4-tert-Butoxy-3-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}butanoic acid (3R)-4-tert-butoxy-3-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}butanoic acid (3R)-4-(tert-butoxy)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanoic acid (R)-4-(1,1-Dimethylethoxy)-3-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]butanoic acid (3R)-3-(9H-fluoren-9-ylmethoxycarbonylamino)-4-[(2-methylpropan-2-yl)oxy]butanoic acid Butanoic acid, 4-(1,1-dimethylethoxy)-3-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-, (3R)-
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CAS | 203854-51-7
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InChI | InChI=1/C23H27NO5/c1-23(2,3)29-13-15(12-21(25)26)24-22(27)28-14-20-18-10-6-4-8-16(18)17-9-5-7-11-19(17)20/h4-11,15,20H,12-14H2,1-3H3,(H,24,27)(H,25,26)/t15-/m1/s1 |
Fmoc-(R)-3-amino-4-(tert-butoxy)butanoic acid - Physico-chemical Properties
Molecular Formula | C23H27NO5
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Molar Mass | 397.46 |
Density | 1.198±0.06 g/cm3(Predicted) |
Melting Point | 96-98℃ |
Boling Point | 599.3±50.0 °C(Predicted) |
Flash Point | 316.2°C |
Vapor Presure | 3.28E-15mmHg at 25°C |
pKa | 4.27±0.10(Predicted) |
Storage Condition | Sealed in dry,2-8°C |
Refractive Index | 1.569 |
Fmoc-(R)-3-amino-4-(tert-butoxy)butanoic acid - Risk and Safety
WGK Germany | 3 |
Hazard Class | IRRITANT |
Fmoc-(R)-3-amino-4-(tert-butoxy)butanoic acid - Introduction
(3R)-4-tert-butoxy-3-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}butanoic acid is a compound whose properties include the appearance of white crystalline powder, molecular formula C28H31NO6, the molecular weight was 477.55g/mol.
(3R)-4-tert-butoxy-3-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}butanoic acid is mainly used as an amino acid protecting group in organic synthesis. It can protect the hydroxyl and amino groups and delay the reaction.
Preparation of (3R)-4-tert-butoxy-3-{[(9H-fluoren-9-ylmethoxy) the method of carbonyl]amino}butanoic acid is to react L-B-homoserine with N-methyl-urotropine and dimethylformamide at low temperature, and then add TERT-butyl protecting agent to react to obtain the product.
For safety information,(3R)-4-tert-butoxy-3-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}butanoic acid should be handled and stored in accordance with general laboratory safety procedures. It may cause irritation to the eyes, skin and respiratory tract, so it is necessary to wear protective equipment such as goggles, gloves and protective masks during use. In addition, should be stored in a cool, dry place, and away from flammable and oxidizing agents.
Last Update:2024-04-10 22:29:15